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Download e-book for kindle: 32nd Hemophilia Symposium: Hamburg 2001 by W. Schramm, H. Krebs (auth.), Professor Dr. med. Inge

By W. Schramm, H. Krebs (auth.), Professor Dr. med. Inge Scharrer, Professor Dr. med. Wolfgang Schramm (eds.)

ISBN-10: 354043884X

ISBN-13: 9783540438847

ISBN-10: 3642181503

ISBN-13: 9783642181504

This e-book comprises the contributions to the thirty second Hemophilia Symposium, Hamburg 2001. the most themes are epidemiology, hemophilia, pediatric hemostasiology. the amount is rounded off through various loose papers and posters on hemophilia, hemorrhagic diathesis, thrombophilic diathesis and linked issues.

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Extra resources for 32nd Hemophilia Symposium: Hamburg 2001

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Table 1. 0 years. The oldest patient is 95,the youngest 2 years old. 96 patients are younger and 387 older than 15 years, information on age is missing in 25 patients. ~OO 350 300 250 200 ISO \00 50 0 O ·I~ years missing 15-99 years Fig. 2. Age Table 2. Type of hemophilia according to counties County Hemotype Hem . 0% 16 U. Eidher et al. HIV infection Unfortunately the data concerning HIV in our 2001 survey is less complete than in the year 2000 so that we used the 2000's survey's data in which 52 patients were HIV infected , 45 with hemophilia A and 7 with hemophilia B.

BRACKMANN, W. SCHRAMM, R. SCHWAAB, and J. GRAW Summary In Germany, approximately 5800 patients are suffering from hemophilia A. In a systematic large-scale analysis we will identify the genotype of all severe cases (approximately 3000 patients). A first screening for mutations causing hemophilia A analyzes the exons from genomic DNA by methods like DGGE,SSCP or dHPLC. Since this approach covers only approximately 97% of the mutations, the FVIII gene of the remaining patients has to be sequenced in total.

A. Donnelly, and R. M. Anderson. Predicted vCJD mortality in Great Britain. Nature 406:583-584, 2000 1/. Genetic Diagnosis ofClotting Disorders Chairmen: E. O. MElLI (Zurich) I. SCHARRER (Frankfurt/Main) 1/ a. Human Genome Project 11 novel Mutations in the Factor VIII encoding Gene lead to severe or moderate Hemophilia A C. DEN, N. KLOPP, J. -H. BRACKMANN, W. SCHRAMM, R. SCHWAAB, and J. GRAW Summary In Germany, approximately 5800 patients are suffering from hemophilia A. In a systematic large-scale analysis we will identify the genotype of all severe cases (approximately 3000 patients).

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32nd Hemophilia Symposium: Hamburg 2001 by W. Schramm, H. Krebs (auth.), Professor Dr. med. Inge Scharrer, Professor Dr. med. Wolfgang Schramm (eds.)


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